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Recombinant Human G-CSF
名稱 Recombinant Human G-CSF
型號
更新時間 2023-09-24
特點 g - csf的造血生長因子刺激承諾祖細胞中性粒細胞的發(fā)展和增強的功能活動end-cell成熟。產(chǎn)生針對特定的刺激多種細胞包括巨噬細胞、成纖維細胞、內(nèi)皮細胞和骨髓基質(zhì)。使用g - csf臨床上促進骨髓移植后造血恢復(fù)。}
  • 詳細內(nèi)容

一.產(chǎn)品名稱:Recombinant Human G-CSF

二.Catalog Number:300-23

Synonyms:

Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin

Description:

G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

AA Sequence:

TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIW MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Cross Reactivity:

Monkey, Mouse, Pig, Human, Plant

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